WebBackground: Sotalol is often employed to prevent recurrence of symptomatic atrial flutter/atrial fibrillation. Because sotalol can prolong the QT interval excessively causing ventricular arrhythmias, a 3-day in-hospital loading or dose escalation period is mandated with oral administration in the product label for patient safety. Note: The generic form of this drug is used for atrial fibrillation or ventricular arrhythmia. The trade name Betapace (R) is for ventricular arrhythmia only and the trade name Betapace AF (R) is for atrial fibrillation only. These two trade names are not interchangeable. SOTALOL: (ATRIAL FIBRILLATION, … See more Usual Adult Dose: Ventricular Arrhythmia: (CA, US): Note: The generic form of this drug is used for atrial fibrillation or ventricular … See more US BOXED WARNING: 1. LIFE-THREATENING PROARRHYTHMIA: This drug can cause life threatening ventricular tachycardia associated with QT interval prolongation. Do not … See more Adults: Oral [Betapace(R)]: 1. CrCl less than 10 mL/min: Dose should be individualized 2. CrCl 10 to 29 mL/min: The dosage interval should be increased to 36 to 48 hours. 3. CrCl 30 to 59 mL/min: The dosage interval … See more Extreme caution should be exercised in patients with renal failure undergoing hemodialysis. The half-life of this drug is prolonged (up to 69 hours) in anuric patients. However, this drug can be partly removed by dialysis … See more
Model-Informed Development of Sotalol Loading and Dose
WebApr 7, 2024 · The investigators conducted DASH-AF, a prospective, nonrandomized, multicenter, open-label trial consisting of patients who underwent IV sotalol loading … buy justin bieber tickets malaysia
Sotalol: Generic, Uses, Side Effects, Dosages, Interactions ... - RxList
WebWe proposed a 1-day IV sotalol loading protocol similar to that proposed by Somberg et al., 11 where an initial IV dose of sotalol was administered over 1 h, followed by the first … WebSep 2, 2024 · Sotalol is a prescription drug indicated for the treatment of life-threatening, documented ventricular arrhythmias, such as sustained ventricular tachycardia (VT). … WebTo minimize the risk of induced arrhythmia, patients initiated or re-initiated on sotalol should be placed for a minimum of 3 days (on their maintenance dose) in a facility that can provide cardiac resuscitation and continuous electrocardiographic monitoring. Monitor serum creatinine, magnesium, potassium, heart rate, blood pressure; EKG. buy just internet service